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The gynecomastia It is a condition characterized by abnormal growth of breast tissue in men and boys. This situation may be the result of hormonal imbalances, where estrogens (female hormones) exceed androgens (male hormones), or it may be associated with various health conditions, such as liver problems, kidney problems, obesity, or the use of certain medications.
There are different treatments for gynecomastia that vary depending on the underlying cause, including changes in medication, hormone therapy, or surgery to remove excess breast tissue. Early detection and consultation with a health professional are key to properly addressing this condition and avoiding complications.
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The first study on gynecomastia, published in the BMJ Opensuggests that men with this condition may have increased risk of premature death before the age of 75. The researchers relied on data from Denmark’s national health and population registries: 23,429 men were diagnosed with gynecomastia between January 1, 1995 and June 30, 2021. Just over 44% were between 19 and 40 years old. at the time of diagnosis.
Each of them was matched by age and date of diagnosis with five randomly selected men without the condition, totaling 140,574. Men with gynecomastia were divided into two groups: those with idiopathic gynecomastia (unknown cause) (16,253); and those with a known pre-existing condition or taking medications associated with gynecomastia (7,176).
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They were all monitored from the date of entry into the study until death or the end of June 2021, whichever comes first. In total, 12,676 (9%) men died during the follow-up period. Among those with gynecomastia, 1,093 (nearly 7%) with the condition of unknown cause and 1,501 (21%) of those with a preexisting risk factor died, compared with 10,532 (9%) deaths among men without gynecomastia. This equates to a 37% higher risk of premature death from any cause among those with gynecomastia than among those without the condition.
However, when stratified by group, the risk of death was higher in those with a pre-existing condition known, among whom the odds were 75% higher than those with gynecomastia of unknown cause, among whom the odds were 5% higher. The men with idiopathic gynecomastia They generally had no greater risk of premature death than men in the reference group, except for a twofold greater risk of death from liver disease due to a specific cause.
Since it is an observational study, cannot establish causal factorsand the researchers acknowledge that they were unable to take into account potentially influential factors, such as obesity, exposure to endocrine-disrupting chemicals, and steroid use.
In this way, the researchers conclude that men diagnosed with gynecomastia have a risk of death a 37% olderobserved primarily in men with a known preexisting gynecomastia risk factor and not in men with idiopathic gynecomastia.
(With information from Europa Press)
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